Related Experiment Videos
[Experimental immunopharmacology of RU 41740]
1Unité de Recherches sur la Pathologie autoimmune (Inserm U.283), Hôpital Cochin, Paris.
Presse Medicale (Paris, France : 1983)
|July 27, 1988
Abstract:
RU 41740 is a biological immunomodulator which stimulates phagocytic cells, mostly by increasing their functional activities: cell metabolism, chemotaxis and secretion of mediators, notably interleukine 1. This compound also stimulates cellular immunity, as shown by the increase observed in proliferative responses in vitro, cell-mediated lymphocytotoxicity and natural killer cell-dependent cytotoxicity. Finally, RU 41740 stimulated B cells through a mitogenic effect and through a non-specific increase in antibody secretion.