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Related Concept Videos

Ideal Solutions02:24

Ideal Solutions

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According to Raoult’s law, the partial vapor pressure of a solvent in a solution is equal or identical to the vapor pressure of the pure solvent multiplied by its mole fraction in the solution. However, Raoult's Law is only valid for ideal solutions. For a solution to be ideal, the solvent-solute interaction must be just as strong as a solvent-solvent or solute-solute interaction. This suggests that both the solute and the solvent would use the same amount of energy to escape to the...
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General Properties of Solutions02:12

General Properties of Solutions

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Many common substances around us exist as a solution, such as ocean water, air, and gasoline. All solutions are mixtures of substances that are composed of varying amounts of two or more types of atoms or molecules. A mixture with a non-uniform composition is a heterogeneous mixture, whereas a mixture with a uniform composition is a homogeneous mixture. The components that make the homogeneous mixture are evenly spread out and thoroughly mixed. 
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Solution Formation02:16

Solution Formation

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There is no one solvent that can dissolve every type of solute. Some substances that readily dissolve in a certain solvent might be insoluble in a different solvent. A simple way to predict which substances dissolve in which solvent is the phrase "like dissolves like". This means that polar substances, such as salt and sugar, dissolve in a polar substance like water. In contrast, non-polar substances are more soluble in non-polar solvents such as carbon tetrachloride.
This selective...
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Enthalpy of Solution02:39

Enthalpy of Solution

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There are two criteria that favor, but do not guarantee, the spontaneous formation of a solution:
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Standard Solutions01:14

Standard Solutions

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Standard solutions refer to solutions with a precisely known concentration or composition. A primary standard is a highly pure, high molar mass, stable substance that is entirely soluble in water, the most commonly used solvent in analytical chemistry. The primary standard solution can be used to standardize secondary standards, which are substances with known concentrations but are less pure and stable. Standard solutions are essential for achieving accurate and reliable results in analytical...
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Blank Solutions00:56

Blank Solutions

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A blank solution is a solution that does not contain the analyte, or the substance of interest being tested or measured. It is typically prepared using the same reagents and procedure as the sample solution but without adding the analyte. The primary purpose of preparing a blank solution is to account for any background interference or contamination that may affect the accuracy and reliability of the analytical method.
In some experimental cases, the reagents, solvents, or lab equipment used in...
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Recurrent candidal intertrigo: challenges and solutions.

Ahmet Metin1, Nursel Dilek2, Serap Gunes Bilgili3

  • 1Department of Dermatology and Venereology, Medical School of Ankara, Yildirim Beyazit University, Ankara, Turkey.

Clinical, Cosmetic and Investigational Dermatology
|May 2, 2018
PubMed
Summary

Intertrigo, an inflammatory skin condition often caused by candida, significantly impacts quality of life. Management focuses on correcting predisposing factors and using topical antifungals like nystatin and azoles.

Keywords:
Candidacandidal predisposalscandidiasiscandidosisintertrigorecurrent candidal intertrigo

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Area of Science:

  • Dermatology
  • Mycology

Background:

  • Intertrigo is a common inflammatory skin condition affecting opposing skin surfaces.
  • It is frequently caused by Candida species, exacerbated by mechanical and environmental factors.
  • Symptoms like pain and itching severely reduce quality of life and contribute to high morbidity.

Purpose of the Study:

  • To review the diagnosis and management of intertrigo, with a focus on candidal intertrigo.
  • To highlight the role of predisposing factors and diagnostic methods.
  • To discuss current and potential therapeutic strategies.

Main Methods:

  • Clinical diagnosis is primary, supported by laboratory tests for confirmation, especially in resistant cases.
  • Identification and management of predisposing factors such as obesity and diabetes are crucial.
  • Treatment involves topical antifungals (nystatin, azoles) and potentially systemic agents for severe cases.

Main Results:

  • Candidal intertrigo diagnosis relies heavily on clinical presentation.
  • Correction of underlying conditions like diabetes and obesity is key to preventing recurrence.
  • Topical antifungals are effective, with systemic options for refractory or widespread infections.

Conclusions:

  • Effective management of intertrigo requires a multifactorial approach, addressing both the infection and predisposing conditions.
  • Early diagnosis and appropriate treatment, including lifestyle modifications, improve patient outcomes.
  • Further research into systemic agents may benefit patients with severe or recurrent candidal intertrigo.