Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

901
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
901
Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

641
During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
641
Bipolar Junction Transistor01:22

Bipolar Junction Transistor

1.5K
Bipolar Junction Transistors (BJTs) are essential elements in electronic circuits, playing a crucial role in the functionality of amplifiers, memories, and microprocessors. These transistors can be designed as NPN or PNP based on their doping patterns. They consist of three layers: the emitter, base, and collector. The configuration of these layers and their respective doping levels—with N-type or P-type impurities—define the transistor's type and its operational...
1.5K
Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

19.6K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.6K
Erikson's Theory on Socioemotional Development during Adolescence01:17

Erikson's Theory on Socioemotional Development during Adolescence

1.3K
Erik Erikson's fifth stage of psychosocial development, "identity versus role confusion," is crucial during adolescence (ages 12 to 18). In this stage, adolescents face the developmental task of forging a distinct personal identity, a process influenced by social, psychological, and biological changes typical of this period. Adolescents naturally explore different roles, behaviors, and ideologies as they navigate complex questions of self-concept, asking, "Who am I?" and "What is my place in...
1.3K
Revisionist Views of Adolescent and Adult Cognition01:24

Revisionist Views of Adolescent and Adult Cognition

316
A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are...
316

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Pragmatic SMART Study of Medication and CBT Sequencing in Pediatric Anxiety Disorders: A Randomized Clinical Trial.

The American journal of psychiatry·2026
Same author

Identifying the Aggression Impulsive/Reactive (AIR) Profile in Youth With Behavioral Challenges.

JAACAP open·2026
Same author

Diagnosis and Medication Treatment of Schizophrenia in Adolescents.

Drugs·2026
Same author

Data Diversity vs. Model Complexity in the Prediction of Pediatric Bipolar Disorder: Evidence from Academic and Community Clinical Samples.

medRxiv : the preprint server for health sciences·2026
Same author

Latent profiles of mood: Toward an empirical definition of mixed mood in youth.

Journal of affective disorders·2026
Same author

Editors' Best of 2025.

JAACAP open·2026

Related Experiment Video

Updated: Feb 11, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.4K

Treating Bipolar Disorder in Adolescents.

Robert L Findling1

  • 1Johns Hopkins University and the Kennedy Krieger Institute, Baltimore, Maryland, USA.

The Journal of Clinical Psychiatry
|May 3, 2018
PubMed
Summary

Choosing bipolar disorder treatments for adolescents involves evaluating lithium, anticonvulsants, and atypical antipsychotics. This report guides clinicians in assessing efficacy, safety, and monitoring adverse effects like weight gain and fatigue.

Area of Science:

  • Child and Adolescent Psychiatry
  • Pharmacology
  • Mental Health Treatment

Background:

  • Bipolar disorder (BD) in adolescents presents unique treatment challenges.
  • Pharmacological interventions are a cornerstone of management.
  • Evidence-based selection requires understanding drug profiles.

Purpose of the Study:

  • To review the efficacy and safety of key pharmacological agents for adolescent bipolar disorder.
  • To provide guidance on selecting appropriate treatments.
  • To highlight common adverse effects and monitoring strategies.

Main Methods:

  • Literature review of studies on lithium, anticonvulsants, and atypical antipsychotics in adolescents.
  • Analysis of efficacy data, safety profiles, and tolerability.

More Related Videos

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

2.7K
Chronic Social Defeat Stress in Early Adolescent Male Mice
07:06

Chronic Social Defeat Stress in Early Adolescent Male Mice

Published on: January 24, 2025

1.6K

Related Experiment Videos

Last Updated: Feb 11, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.4K
Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

2.7K
Chronic Social Defeat Stress in Early Adolescent Male Mice
07:06

Chronic Social Defeat Stress in Early Adolescent Male Mice

Published on: January 24, 2025

1.6K
  • Synthesis of clinical guidelines for adverse event monitoring.

    • Main Results:

    • Lithium, anticonvulsants, and atypical antipsychotics demonstrate varying efficacy and side effect profiles.
    • Weight gain and fatigue are common adverse effects requiring vigilant monitoring.
    • Individualized treatment selection is crucial based on patient characteristics and response.

    Conclusions:

    • Careful consideration of efficacy, safety, and tolerability is essential for treatment selection.
    • Proactive monitoring for adverse effects improves patient outcomes.
    • A multimodal approach may be necessary for comprehensive adolescent bipolar disorder management.