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Manufacture and Drug Delivery Applications of Silk Nanoparticles
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Mesoporous silica nanoparticles for drug and gene delivery

Yixian Zhou1, Guilan Quan1, Qiaoli Wu2

  • 1School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.

Acta Pharmaceutica Sinica. B
|May 3, 2018
PubMed

Keywords:
AO, acridine orangeAPTES, 3-aminopropyltriethoxysilaneAPTMS, amino propyl trimethoxysilaneBCL-2, B-cell lymphoma-2BCS, Biopharmaceutical Classification SystemBio-TEM, biological transmission electron microscopyC dots, Cornell dotsCMC, critical micelle concentrationCPT, camptothecinCTAB, cetyltrimethyl ammonium bromideCancer therapyEPR, enhanced permeability and retentionFDA, Food and Drug AdministrationGI, gastrointestinalGNRs@mSiO2, mesoporous silica-encapsulated gold nanorodsGene deliveryLHRH, luteinising-hormone releasing hormoneMDR, multi-drug resistanceMRP1, multidrug resistance protein 1MSN-Dox-G2, Dox-loaded and G2 PAMAM-modified MSNsMSNs, mesoporous silica nanoparticlesMSNs-HA, hyaluronic acid-conjugated MSNsMSNs-RGD/TAT, RGD/TAT peptide-modified MSNsMSNs-TAT, TAT peptide-modified MSNsMSNs@PDA-PEG-FA, poly(ethylene glycol)-folic acid-functionalized polydopamine-modified MSNsMTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromideMesoporous silica nanoparticlesMultidrug resistanceNIR, near-infraredP-gp, P-glycoproteinPAMAM, polyamidoaminePDEAEMA, poly (2-(diethylamino)ethylmethacrylate)PDMAEMA, poly(2-(dimethylamino)ethylmethacrylate)PEG400, polyethylene glycol 400PEI, polyethyleneiminePLL, poly-l-lysinePTX, paclitaxelPoorly soluble drugQ-MSNs, quercetin encapsulated MSNsRGD, arginine-glycine-aspartateTAT, trans-activating transcriptorTMB, 1,3,5-trimethybenzenepDNA, plasmid DNA

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