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Related Experiment Video

Updated: Feb 11, 2026

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

Published on: June 3, 2013

18.0K

Hemicrania Continua.

Sanjay Prakash1, Bansi Adroja2

  • 1Department of Neurology, Smt. B. K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth University, Vadodara, Gujarat, India.

Annals of Indian Academy of Neurology
|May 4, 2018
PubMed
Summary
This summary is machine-generated.

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Hemicrania continua (HC) is a continuous, strictly unilateral headache disorder. Complete response to indomethacin is key for diagnosis, though misdiagnosis is common.

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Hemicrania continua (HC) is a primary chronic headache disorder and a subtype of trigeminal autonomic cephalalgias (TACs).
  • It affects 1.7% of headache patients and is frequently misdiagnosed, even by specialists.
  • HC presents as continuous, strictly unilateral headaches with superimposed exacerbations, often accompanied by autonomic symptoms and sometimes migrainous features.

Purpose of the Study:

  • To highlight the diagnostic challenges and key features of Hemicrania Continua.
  • To emphasize the diagnostic significance of indomethacin responsiveness.
  • To discuss differential diagnoses and treatment considerations for HC.

Main Methods:

  • Literature review of >1000 reported cases of HC.
  • Analysis of clinical presentation, diagnostic criteria, and treatment responses.
Keywords:
Hemicrania continuaindomethacinindomethacin-responsive headachetrigeminal autonomic cephalalgias

Related Experiment Videos

Last Updated: Feb 11, 2026

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

Published on: June 3, 2013

18.0K
  • Comparison with other primary and secondary headache disorders.

    • Main Results:

    • HC is characterized by continuous unilateral pain and exacerbations with autonomic symptoms.
    • Migraine and cluster headache are common misdiagnoses.
    • A complete response to indomethacin is considered pathognomonic for HC.
    • Other medications and surgical procedures have shown variable success.

    Conclusions:

    • Accurate diagnosis of HC requires recognizing the persistent background headache and characteristic response to indomethacin.
    • Distinguishing HC from other headache disorders is crucial for effective management.
    • Indomethacin remains the cornerstone of treatment for Hemicrania Continua.