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Epstein-Barr Virus-Positive Mucocutaneous Ulcer in an Immunosuppressed Patient

Isabel A Hujoel1, Alberto Rubio-Tapia2, Linda N Dao3

  • 1Division of Internal Medicine, Mayo Clinic, Rochester, MN.

ACG Case Reports Journal
|May 4, 2018
PubMed

Immunosuppressive medications, frequently used to treat inflammatory bowel disease, have been linked to the development of Epstein-Barr virus (EBV)-associated lymphoproliferative disorders (LPD). We describe a case of an EBV-positive mucocutaneous ulcer involving the palate in an elderly woman with inactive Crohn's disease. This patient had been on high-dose azathioprine for a decade. Following diagnosis of her LPD and discontinuation of azathioprine, her oral ulcers resolved completely.

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