Related Experiment Video
Updated: Feb 11, 2026

Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery
Published on: March 4, 2021
Hydroxychloroquine retinal toxicity in two patients with dermatological conditions
Tanya Kowalski1, Christopher Baker2, Heather G Mack3,4
1Alfred Hospital, Melbourne, Victoria, Australia.
Abstract:
Two patients with dermatological conditions developed retinal toxicity after treatment with hydroxychloroquine that exceeded dosing recommendations. There is no treatment for hydroxychloroquine retinal toxicity and associated visual loss, so appropriate monitoring is imperative. All members of a patient's multidisciplinary team should be aware of the ocular risks of hydroxychloroquine, the importance of dosing within recommended guidelines and appropriate monitoring in reducing the risk of visual loss.
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