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Updated: Feb 11, 2026

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Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
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[Erectile dysfunction and psychological status in infertile males]
Jian-Xiong Ma1, Bin Wang1, Jin Dang1
1Department of Andrology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Summary
Male infertility is linked to higher rates of erectile dysfunction (ED), depression, and anxiety compared to fertile men. Psychological factors significantly impact ED prevalence in infertile individuals.
Area of Science:
- Reproductive Medicine
- Men's Health
- Psychology
Background:
- Male infertility affects a significant portion of the reproductive-aged population.
- Psychological distress, including depression and anxiety, is increasingly recognized in men with infertility.
- Erectile dysfunction (ED) is a common concern that can impact quality of life and relationships.
Purpose of the Study:
- To investigate the relationship between erectile dysfunction (ED) and psychological factors in male patients experiencing infertility.
- To compare the prevalence of ED, depression, and anxiety in infertile men versus fertile controls.
Main Methods:
- A questionnaire-based study was conducted on 252 infertile male patients and 100 fertile male controls.
- Data collected included general information, semen analysis, sexual function (IIEF-5), depression (PHQ-9), and anxiety (GAD-7) scores.
- Statistical analyses, including logistic regression, were used to determine correlations and risk factors.
Main Results:
- Infertile men exhibited significantly higher rates of depression (20.4%) and anxiety (42.9%) compared to fertile controls.
- The incidence of ED was higher in infertile men (28.6%) than in fertile men (12.4%), with lower IIEF-5 scores and sexual satisfaction.
- Psychological distress (higher PHQ-9 and GAD-7 scores) was strongly associated with ED in infertile patients.
Conclusions:
- Male infertility patients demonstrate poorer mental health and a higher prevalence of ED than fertile men.
- Psychological status and ED prevalence are interconnected in infertile men.
- Identifying and addressing psychological factors is crucial for managing ED in infertile populations.
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