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[Antioxidant vitamins in asthma].

Columba Citlalli Barrera-Mendoza1, Francisco Ayala-Mata, Christian Cortés-Rojo

  • 1Instituto de Investigaciones Científicas en Temas de Familia, Alergia e Inmunología, Morelia, Michoacán, México. rodriguez.orozco.ar.2011@gmail.com.

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|May 4, 2018
PubMed
Summary

The role of antioxidant vitamins A, C, D, and E in asthma management remains unclear. Current research suggests more controlled trials are needed to determine if these vitamin supplements benefit asthma control.

Keywords:
Antioxidant vitaminsAsthmaOxidative stress

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Area of Science:

  • Respiratory Medicine
  • Nutritional Science
  • Oxidative Stress Research

Background:

  • Asthma is a chronic airway inflammatory disease with unknown causes.
  • Inflammation in asthma generates reactive oxygen species, leading to oxidative stress.
  • Oxidative stress may be mitigated by antioxidant vitamins (A, C, D, E).

Purpose of the Study:

  • To review observational and placebo-controlled trials on antioxidant vitamins and asthma.
  • To assess the potential clinical benefits of antioxidant vitamin supplementation for asthma control.

Main Methods:

  • Systematic review of studies published between 1979 and 2016.
  • Searches conducted on Google and Google Scholar.
  • Relevant articles identified through PubMed and The Cochrane Library.

Main Results:

  • 75 relevant articles were reviewed.
  • Evidence regarding the beneficial effect of antioxidant vitamin supplements on asthma control is inconclusive.
  • The precise role of these nutrients in asthma management requires further investigation.

Conclusions:

  • The clinical efficacy of antioxidant vitamin supplements for improving asthma control is not established.
  • Further well-controlled, long-term clinical trials are necessary to clarify the role of antioxidant vitamins in asthma.
  • Current evidence does not support routine supplementation for asthma management.