Related Experiment Video
Updated: Feb 11, 2026

Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia
Published on: March 20, 2018
A Systematic Review of Studies Using the Multidimensional Assessment of Fatigue Scale
Purpose:
To review how the Multidimensional Assessment of Fatigue (MAF) has been used and evaluate its psychometric properties.
Methods:
We conducted a database search using "multidimensional assessment of fatigue" or "MAF" as key terms from 1993 to 2015, and located 102 studies.
Results:
Eighty-three were empirical studies and 19 were reviews/evaluations. Research was conducted in 17 countries; 32 diseases were represented. Nine language versions of the MAF were used. The mean of the Global Fatigue Index ranged from 10.9 to 49.4. The MAF was reported to be easy-to-use, had strong reliability and validity, and was used in populations who spoke languages other than English.
Conclusion:
The MAF is an acceptable assessment tool to measure fatigue and intervention effectiveness in various languages, diseases, and settings across the world.
Related Concept Videos
Fatigue
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
pH Scale
Random and Systematic Errors
Muscle Recovery and Fatigue

