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Updated: Feb 11, 2026

Application of AlDeSense to Stratify Ovarian Cancer Cells Based on Aldehyde Dehydrogenase 1A1 Activity
Published on: March 31, 2023
Impact of Aldehyde Dehydrogenase Activity on Gliomas
Theodora Vasilogiannakopoulou1, Christina Piperi1, Athanasios G Papavassiliou2
1Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece; These authors contributed equally to this work.
Abstract:
High-grade gliomas are primary brain tumors with a highly aggressive, invasive phenotype and dismal outcome. Targeting cell metabolism and cancer bioenergetics has emerged as a potential effective therapeutic approach. Selective aldehyde dehydrogenase isoenzyme activity regulates glioma tumor growth, invasiveness, and resistance to current treatments, and has potential as a therapeutic target.
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