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Pediatric Iatrogenic Movement Disorders
Deepti Nagesh1, Marcie Goeden1, Keith A Coffman1
1Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO.
Insights
A thorough medication history is critical for diagnosing acute movement disorders. Many drugs, not just psychoactive ones, can cause iatrogenic movement disorders, requiring careful patient evaluation.
Area of Science:
- Neurology
- Pharmacology
Background:
- Acute movement disorders present dramatically, necessitating urgent neurological evaluation.
- Diagnosis relies on history, physical, and neurological examination.
Purpose of the Study:
- To highlight the critical role of comprehensive medication history in diagnosing iatrogenic movement disorders.
- To emphasize that non-neurologic medications can also cause movement disorders.
Main Methods:
- Comprehensive review of literature.
- Organized content by movement disorder semiology.
Main Results:
- Iatrogenic movement disorders stem from a wide range of medications, including those for non-neurologic conditions.
- A structured approach by semiology aids differential diagnosis.
Conclusions:
- A detailed medication history is essential for identifying drug-induced movement disorders.
- Neurologists must consider all prescribed medications when evaluating patients with new-onset movement abnormalities.
Abstract:
The acute development of a movement disorder is often a dramatic and frightening experience for patients and families, often requiring urgent or emergent evaluation by a neurologist. In the assessment of these patients, one relies on the history, physical and neurologic examination to determine the etiology of the condition. We aim to demonstrate that a thorough medication history is an incredibly critical part of this evaluation as iatrogenic movement disorders can arise from exposure not only to psychoactive medications, but from drugs prescribed for a variety of nonneurologic disorders. This comprehensive review is organized by movement disorder semiology so that the reader can more readily develop a differential diagnosis when evaluating a patient with a movement disorder.
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