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Pain01:20

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Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Related Experiment Video

Updated: Feb 11, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
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Evidence-Based Nonpharmacologic Strategies for Comprehensive Pain Care: The Consortium Pain Task Force White Paper.

Heather Tick1, Arya Nielsen2, Kenneth R Pelletier3

  • 1Departments of Family Medicine, Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, WA.

Explore (New York, N.Y.)
|May 9, 2018
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Summary

The medical pain management crisis requires a shift from opioids to evidence-based nonpharmacologic therapies. These strategies, including acupuncture and mind-body interventions, offer effective, safer alternatives for various pain types.

Keywords:
Acute Pain ManagementChronic Pain ManagementEvidence-Based Practice in Health Care SystemIntegrative MedicineNon Surgical Pain ManagementPublic Health

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Area of Science:

  • Pain Medicine
  • Integrative Health
  • Public Health

Background:

  • Current medical pain management faces a crisis due to opioid overuse, addiction, and ineffective treatments.
  • Rising healthcare costs and adverse effects necessitate a paradigm shift towards comprehensive pain care.
  • Federal and state agencies are urging a move away from opioid reliance towards evidence-based nonpharmacologic options.

Purpose of the Study:

  • To provide a comprehensive overview of the current pain management crisis.
  • To detail the evidence-base for nonpharmacologic therapies across various pain conditions.
  • To advocate for the integration of effective nonpharmacologic strategies into pain care models.

Main Methods:

  • Review of historical context and magnitude of the pain problem.
  • Analysis of individual, social, and economic impacts of pain.
  • Evidence-based review of nonpharmacologic therapies for postsurgical, acute, cancer, and chronic pain.

Main Results:

  • Nonpharmacologic therapies like acupuncture, massage, mind-body interventions, and self-care strategies are effective for various pain types.
  • These therapies offer opioid-sparing benefits and reduced risks of adverse events and addiction.
  • Evidence supports the efficacy of nonpharmacologic approaches in postsurgical, acute, cancer, and chronic pain management.

Conclusions:

  • A comprehensive pain care model must integrate evidence-based nonpharmacologic strategies.
  • Increased awareness, practitioner training, policy reform, and research are crucial for implementing effective nonpharmacologic pain care.
  • Shifting to nonpharmacologic options reduces risks, improves patient outcomes, and addresses the opioid crisis.