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2017 FDA Peptide Harvest.

Othman Al Musaimi1,2, Danah Al Shaer3,4, Beatriz G de la Torre5

  • 1College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa. musamiau@gmail.com.

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Summary

In 2017, the FDA approved 46 new drugs, including six innovative peptide therapeutics. This analysis details their chemical structures, synthesis, sources, therapeutic applications, and mechanisms of action.

Keywords:
drug discoverydrugspharmaceutical marketsolid-phase peptide synthesis

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Area of Science:

  • Pharmaceutical Sciences
  • Medicinal Chemistry
  • Drug Discovery

Background:

  • The year 2017 saw a significant number of new drug approvals by the U.S. Food and Drug Administration (FDA).
  • Among these approvals, a notable increase in the number of peptide-based therapeutics was observed.

Purpose of the Study:

  • To analyze the six peptide drugs approved by the FDA in 2017.
  • To provide a comprehensive overview of their chemical characteristics, production methods, origins, clinical uses, and functional mechanisms.

Main Methods:

  • Literature review and data compilation of FDA-approved drugs in 2017.
  • Analysis of chemical structure and synthetic strategies for peptide drugs.
  • Categorization based on therapeutic area and mechanism of action.

Main Results:

  • Six peptide drugs were approved in 2017, representing a key trend in drug development.
  • Detailed information on the chemical nature, synthesis routes, and biological sources of these peptides was gathered.
  • The therapeutic applications and modes of action for each peptide were elucidated.

Conclusions:

  • The 2017 FDA approvals highlight the growing importance and versatility of peptide therapeutics.
  • Understanding the diverse characteristics of these peptide drugs is crucial for future drug design and development.
  • This analysis provides valuable insights into the landscape of peptide-based medicines.