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Related Experiment Video

Updated: Feb 10, 2026

Ex Vivo Perfusion of the Rodent Placenta
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A Case of Placenta Percreta Managed with Sequential Embolisation Procedures.

Shannon Armstrong-Kempter1,2, Supuni Kapurubandara1,3,4, Brian Trudinger3

  • 1Department of Women's and Newborn Health, Westmead Hospital, Westmead, NSW 2145, Australia.

Case Reports in Obstetrics and Gynecology
|May 9, 2018
PubMed
Summary

This case study shows that sequential uterine artery embolisation (UAE) can be a safe and effective primary treatment for placenta percreta, even with bladder involvement. Repeat UAE reduced placental perfusion, avoiding hysterectomy.

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Area of Science:

  • Reproductive Medicine
  • Interventional Radiology
  • Maternal-Fetal Medicine

Background:

  • Rising cesarean section rates correlate with increased placenta percreta incidence.
  • Traditional management involves cesarean hysterectomy, carrying significant risks.
  • Uterine artery embolisation (UAE) offers a minimally invasive alternative to reduce placental perfusion.

Observation:

  • A rare case of placenta percreta with bladder involvement was successfully managed.
  • The patient underwent four sequential UAE procedures over 248 days.
  • No major morbidities or complications were observed during the treatment course.

Findings:

  • Sequential UAE effectively decreased placental perfusion.
  • This approach facilitated placental resorption.
  • The patient avoided hysterectomy, preserving reproductive potential.

Implications:

  • Repeat UAE is a viable primary management strategy for placenta percreta.
  • This technique may reduce hemorrhage and associated morbidities.
  • UAE presents a promising alternative for managing complex placental abnormalities.