Related Experiment Video
Updated: Aug 12, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
The Maryland experience: angioplasty and valvuloplasty using percutaneous cardiopulmonary support
1Division of Cardiology, University of Maryland Hospital, Baltimore 21201.
Abstract:
Vessel closure during coronary angioplasty in patients with poor ventricular function or extensive distribution of the target vessel, or both, can result in hemodynamic collapse--a potentially fatal complication. A similar situation can develop as a result of problems arising during aortic valvuloplasty. In an attempt to extend the benefits of angioplasty and valvuloplasty to patients with more advanced coronary and valvular heart disease, semipercutaneous cardiopulmonary circulatory support has been used as an adjunct to these interventions. In our initial experience with supported angioplasty/valvuloplasty, 11 vessels in 9 patients and 6 aortic valves were successfully dilated. Complete cardiopulmonary support was achieved in all cases, permitting prolonged balloon inflations; intraprocedural complications were limited to vessel injury and blood loss. One patient each died after angioplasty and valvuloplasty. Symptomatic improvement was observed in all surviving patients.
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Mitral Stenosis III: Medical Management
Coronary Artery Disease V: Interprofessional Care
Cardiomyopathy V: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care

