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Acute Disseminated Encephalomyelitis Following Meningococcal Vaccination: Case Report and Review of the Literature

Rosana Gnanajothy, Lauren Frederic Visserman, Kanaga N Sena

    Connecticut Medicine
    |May 9, 2018
    PubMed

    Insights

    Acute disseminated encephalomyelitis (ADEM) is a rare central nervous system demyelinating disease that can occur after meningococcal vaccination. Prompt steroid treatment led to full neurological recovery in a 17-year-old patient.

    Area of Science:

    • Neurology
    • Immunology
    • Vaccinology

    Background:

    • Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated demyelinating disease of the central nervous system.
    • Vaccinations, including meningococcal vaccines, are known potential triggers for ADEM, though causality is complex.
    • Early recognition and management are crucial for favorable outcomes in ADEM.

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