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Methylphenidate Induced Lip and Tongue Biting.
Cem Gokcen1, Mehmet Karadag1, Ihsan Aksoy2
1Department of Child and Adolescent Psychiatry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.
Summary
Attention deficit hyperactivity disorder (ADHD) treatment with methylphenidate can cause compulsive lip and tongue biting. This atypical side effect may impact treatment adherence in patients with ADHD.
Area of Science:
- Neuroscience
- Pharmacology
- Psychiatry
Background:
- Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder.
- Pharmacotherapy, particularly stimulant medications, is a primary treatment for ADHD due to its biological basis.
- Stimulant drugs, while effective, are associated with a range of potential side effects.
Observation:
- A patient experienced recurrent lip and tongue biting incidents while on different formulations and dosages of methylphenidate (OROS MPH and IR MPH).
- The biting behaviors occurred with OROS MPH 36 mg/day, IR MPH 10 mg/day, and IR MPH 20 mg/day, affecting the tongue tip, lower lip, and lateral tongue.
Findings:
- Neurological examination and electroencephalography ruled out epilepsy as the cause of the biting behaviors.
- The lip and tongue biting were identified as atypical side effects of methylphenidate, potentially related to perseverative/compulsive behaviors or movement disorders.
Implications:
- Clinicians must be aware of the potential for stimulant medications to induce lip and tongue biting.
- Recognizing this adverse effect is crucial for maintaining treatment compliance in patients with ADHD.
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