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Updated: Feb 10, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
Massive hemoptysis successfully treated with extracorporeal membrane oxygenation and endobronchial thrombolysis
Antônio Aurélio de Paiva Fagundes Júnior1, Renato Bueno Chaves2, Amanda Robassini Dos Santos2
1Unidade de Terapia Intensiva, Hospital Ortopédico e Medicina Especializada, Brasília, DF, Brasil.
Abstract:
Extracorporeal membrane oxygenation has been used to treat refractory hypoxemia in numerous clinical scenarios. The fundamental principles for the management of massive hemoptysis patients include protecting the airway and healthy lung, locating the source of bleeding and controlling the hemorrhage. We report the case of a patient with acute respiratory failure associated with massive hemoptysis secondary to lung laceration during cardiac surgery. The use of extracorporeal membrane oxygenation allowed patient survival. However, due to the great difficulty in managing pulmonary clots after hemoptysis, it was necessary to use an unusual therapy involving endobronchial infusion of a thrombolytic agent as described in rare cases in the literature.
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