Prolonged QRS Widening After Aripiprazole Overdose

Maryann Mazer-Amirshahi1,2, Robert Porter3, Kayla Dewey1,2

  • 1From the Department of Emergency Medicine, MedStar Washington Hospital Center.

Summary

Aripiprazole overdose in a CYP2D6 poor metabolizer adolescent caused prolonged QRS widening without cardiac compromise. Toxicity duration was extended in this patient with genetic variation affecting drug metabolism.

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