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Racial disparities in children tested for SARS-CoV-2 at pediatric emergency departments: A prospective cohort study
Gabrielle Freire1,2, Vikram Sabhaney3,4, April Kam5
1Division of Emergency Medicine, Department of Pediatrics, Faculty of Medicine, University of Toronto, Ontario, Canada.
Insights
Racial disparities in children are linked to higher SARS-CoV-2 (the virus that causes COVID-19) test positivity and varied health outcomes. Understanding these differences is crucial for equitable pediatric healthcare.
Area of Science:
- Pediatric Infectious Diseases
- Health Equity Research
- Epidemiology
Background:
- Racial and ethnic disparities in healthcare access and outcomes are well-documented.
- The impact of race on pediatric SARS-CoV-2 (the virus that causes COVID-19) infection rates and subsequent health outcomes requires further investigation.
Purpose of the Study:
- To examine the association between race and SARS-CoV-2 test positivity in children.
- To evaluate racial differences in medical interventions, hospitalization, and post-COVID condition (PCC) among pediatric patients.
Main Methods:
- Secondary analysis of a prospective cohort study involving children under 18 years old tested for SARS-CoV-2.
- Data collected from Canadian pediatric emergency departments between August 2020 and February 2022.
- Multi-level logistic regression models used to assess associations between self-reported race and outcomes.
Main Results:
- Most racial minority groups showed higher odds of testing positive for SARS-CoV-2 compared to White children.
- Indigenous children had higher odds of hospitalization, while Black children had lower odds of reporting PCC.
- Racial disparities were observed in medical interventions, with minority groups having lower odds.
Conclusions:
- Significant racial disparities exist in SARS-CoV-2 test positivity and health outcomes among Canadian children.
- Further research is needed to understand the contributing factors to these disparities and promote health equity.
Objectives:
To evaluate the association between race and SARS-CoV-2 test positivity and outcomes in children.
Study Design:
Secondary analysis of a prospective cohort study recruiting children < 18 years, tested for SARS-CoV-2 between August 2020 and February 2022, in Canadian pediatric emergency departments. Race was self-reported by participants. The primary outcome was SARS-CoV-2 test positivity. Secondary outcomes were medical interventions and hospitalization within 14 days of index visit, and post-COVID condition (PCC) at 90-day follow-up. Associations were evaluated using multi-level logistic regression models.
Results:
Seven thousand and two-thirty three children underwent SARS-CoV-2 testing; median age was 2.0 years (IQR: 1.0-5.0), and 3366 (46.5%) were female. 1440 (19.9%) children tested positive for SARS-CoV-2, 776 (10.7%) were hospitalized, and 153 (13.2%) test-positive children experienced PCC. Compared to White children, most racial minority groups were more likely to test positive for SARS-CoV-2 (Middle Eastern aOR [95% CI] 2.62 [2.07, 3.32], Black aOR 2.36 [1.85, 3.03], Latin American aOR 2.23 [1.58, 3.15], South Asian aOR 2.17 [1.67, 2.82], Indigenous aOR 2.09 [1.29, 3.37], Southeast Asian aOR 1.82 [1.27, 2.62], Multiracial aOR 1.35 [1.07, 1.69], and had lower odds of medical interventions. Only Indigenous children were at higher odds of hospitalization than White children (aOR [95% CI]: 2.48 [1.03, 5.95]). Black children were less likely to report PCCs than White children (aOR 0.44 [0.22-0.86]).
Conclusions:
Racial disparities exist in SARS-CoV-2 test positivity and outcomes among Canadian children seeking emergency care. A better understanding of the factors contributing to these differences is needed to promote equitable health across the population.
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