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Updated: Feb 10, 2026

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Taking Respect Seriously: Clinical Research and the Demands of Informed Consent
1Oregon Health & Science University, Portland, Oregon, USA.
The Journal of Medicine and Philosophy
|May 11, 2018
Summary
Informed consent in clinical research is crucial for respecting persons. This article defends the necessity of informed consent, even when subjects may not fully comprehend all details, emphasizing autonomous authorization.
Area of Science:
- Bioethics
- Clinical Research Ethics
Background:
- Informed consent is a cornerstone of ethical research, rooted in respecting individual autonomy.
- Recent critiques challenge the necessity of full comprehension of risks and benefits for valid informed consent.
Purpose of the Study:
- To reevaluate the requirements of informed consent in clinical research.
- To address and rebut recent challenges to the doctrine of informed consent.
Main Methods:
- Philosophical analysis of ethical arguments concerning informed consent.
- Critique of recent challenges to established principles of informed consent.
Main Results:
- The article rebuts key arguments from critics of informed consent.
- It demonstrates that core tenets of informed consent, particularly autonomous authorization, remain valid despite critiques.
Conclusions:
- Respect for persons necessitates robust informed consent processes in clinical research.
- While some critiques highlight areas for nuanced discussion, the fundamental importance of autonomous authorization is reaffirmed.
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