[Pyoderma gangrenosum following hematopoietic stem cell transplantation].

Area of Science:

• Dermatology
• Hematology
• Oncology

Background:

• Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis.
• It is associated with systemic diseases, including blood disorders like monoclonal gammopathy and acute myeloid leukemia (AML).
• Blood diseases account for 3.5% of PG cases.

Observation:

• A case of pyoderma gangrenosum is reported in a female patient.
• The patient had undergone a bone marrow transplant (hematopoietic stem cell allograft) six months prior.
• The transplant was part of her treatment for acute T-cell leukemia.

Findings:

• Pyoderma gangrenosum developed in a patient post-hematopoietic stem cell allograft.
• This indicates a potential dermatological complication in patients with a history of leukemia and bone marrow transplantation.

Implications:

• Pyoderma gangrenosum is a recognized complication in bone marrow transplant recipients.
• This case underscores the importance of considering PG in the differential diagnosis of skin lesions in these patients.
• Further research may elucidate the mechanisms linking bone marrow transplantation and PG development.