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Updated: Feb 10, 2026

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes
Published on: August 20, 2007
Personalized epigenetic management of diabetes
Adriana Fodor1,2, Angela Cozma1,3, Eddy Karnieli4
1University of Medicine & Pharmacy 'Iuliu Hatieganu', Cluj-Napoca, Romania.
Abstract:
The novel genome-wide assays of epigenetic marks have resulted in a greater understanding of how genetics and the environment interact in the development and inheritance of diabetes. Chronic hyperglycemia induces epigenetic changes in multiple organs, contributing to diabetic complications. Specific epigenetic-modifying compounds have been developed to erase these modifications, possibly slowing down the onset of diabetes-related complications. The current review is an update of the previously published paper, describing the most recent advances in the epigenetics of diabetes.
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