Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Defenses Against Pathogens and Herbivores02:26

Defenses Against Pathogens and Herbivores

29.7K
Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
29.7K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

2.9K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
2.9K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

2.1K
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
2.1K
Yeast Signaling01:28

Yeast Signaling

17.3K
Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
17.3K
G-protein Coupled Receptors01:21

G-protein Coupled Receptors

132.1K
G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.
132.1K
Riboswitches01:56

Riboswitches

9.8K
Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
9.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PlantGIFT: An effective teacher workshop model for translating experimental STEM research into hands-on classroom activities for middle and high school students.

Journal of college science teaching·2026
Same author

PLANTGIFT: AN EFFECTIVE TEACHER WORKSHOP MODEL FOR INCREASING PLANT-BASED LABORATORY EXPERIENCES IN SECONDARY SCIENCE CLASSROOMS.

International journal of education·2026
Same author

Molecular, Microbial, and Ecological Drivers of Duckweed Phytoremediation in Aquatic Environments.

Biology·2026
Same author

Application of deep learning in crop research: From genomics to phenomics.

The plant genome·2026
Same authorSame journal

Small peptides guard the gate of plant immunity.

Trends in plant science·2026
Same author

Protein Stability, Turnover Kinetics, and Abundance Constrain the Scaling of Protein Interaction Networks.

bioRxiv : the preprint server for biology·2026
Same journal

Better breeding leveraging more biology.

Trends in plant science·2026
Same journal

Women in plant science around the world.

Trends in plant science·2026
Same journal

Bilateral symmetry genes: If they exist, how would we know?

Trends in plant science·2026
Same journal

From xylem atlases to developmental continuity in forestry.

Trends in plant science·2026
Same journal

Phosphorylation blues: Cracking the phototropin phosphocode.

Trends in plant science·2026
See all related articles

Related Experiment Video

Updated: Feb 10, 2026

Unravelling the Function of a Bacterial Effector from a Non-cultivable Plant Pathogen Using a Yeast Two-hybrid Screen
11:30

Unravelling the Function of a Bacterial Effector from a Non-cultivable Plant Pathogen Using a Yeast Two-hybrid Screen

Published on: January 20, 2017

12.1K

NPR1 in JazzSet with Pathogen Effectors.

Yali Sun1, Thomas Ward Detchemendy1, Karolina Marta Pajerowska-Mukhtar1

  • 1Department of Biology, University of Alabama at Birmingham, AL 35294, USA.

Trends in Plant Science
|May 14, 2018
PubMed
Summary
This summary is machine-generated.

Pathogen effectors interfere with NON-EXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1) function to cause plant disease. NPR1 is crucial for salicylic acid-mediated disease resistance in plants.

Keywords:
NF-κBNPR1Pathogen effectorsPlant signaling and immunity

More Related Videos

Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens
10:19

Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens

Published on: February 3, 2020

6.9K
Electroporation of Functional Bacterial Effectors into Mammalian Cells
08:39

Electroporation of Functional Bacterial Effectors into Mammalian Cells

Published on: January 19, 2015

10.5K

Related Experiment Videos

Last Updated: Feb 10, 2026

Unravelling the Function of a Bacterial Effector from a Non-cultivable Plant Pathogen Using a Yeast Two-hybrid Screen
11:30

Unravelling the Function of a Bacterial Effector from a Non-cultivable Plant Pathogen Using a Yeast Two-hybrid Screen

Published on: January 20, 2017

12.1K
Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens
10:19

Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens

Published on: February 3, 2020

6.9K
Electroporation of Functional Bacterial Effectors into Mammalian Cells
08:39

Electroporation of Functional Bacterial Effectors into Mammalian Cells

Published on: January 19, 2015

10.5K

Area of Science:

  • Plant immunity
  • Molecular plant pathology
  • Plant-microbe interactions

Background:

  • NON-EXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1) is a key regulator of plant defense.
  • Salicylic acid (SA) signaling activates systemic acquired resistance (SAR), a broad-spectrum plant immunity mechanism.
  • NPR1 controls a significant portion of the SA-dependent transcriptome in Arabidopsis.

Purpose of the Study:

  • To elucidate mechanisms by which pathogen effectors target NPR1.
  • To understand how NPR1 function is manipulated in different cellular compartments.
  • To explain how NPR1 manipulation contributes to disease establishment in plants.

Main Methods:

  • Review of existing literature on NPR1 function and pathogen interactions.
  • Analysis of molecular pathways involving NPR1 and SA signaling.
  • Discussion of cellular localization and effector-host protein interactions.

Main Results:

  • Pathogen effectors actively target and manipulate NPR1 function.
  • NPR1's role is modulated within specific cellular compartments by effectors.
  • These manipulations disrupt plant defense, facilitating pathogen infection.

Conclusions:

  • NPR1 is a critical hub for pathogen effector interference.
  • Understanding effector-NPR1 interactions is vital for developing disease-resistant crops.
  • Targeting NPR1 is a common strategy employed by pathogens to overcome plant immunity.