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Autoimmunity Mimics: Infection and Malignancy
Jeffrey C Eickhoff1, Angelique N Collamer2
1Rheumatology Service, U.S. Navy, Medical Corps, Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708, USA.
Abstract:
Musculoskeletal rheumatic syndromes are commonly encountered in the primary care setting. A plethora of commonly encountered and rare infectious agents can produce osteoarticular and soft tissue manifestations. Likewise, malignancies may manifest rheumatic symptoms via direct tumor invasion or paraneoplastic effects. Awareness of these diseases and their clinical risk factors should result in improved screening and earlier recognition and intervention, leading to improved long-term outcomes and overall patient care.
Insights
Musculoskeletal rheumatic syndromes in primary care can stem from infections or malignancies. Early recognition of these conditions and their risk factors improves patient outcomes.
Area of Science:
- Rheumatology
- Infectious Diseases
- Oncology
Background:
- Musculoskeletal rheumatic syndromes are frequent in primary care.
- Infectious agents and malignancies can cause rheumatic symptoms.
Purpose of the Study:
- To highlight the diverse causes of rheumatic syndromes in primary care.
- To emphasize the importance of recognizing risk factors for timely intervention.
Main Methods:
- Literature review of infectious and malignant causes of rheumatic syndromes.
- Analysis of clinical presentation and risk factors.
Main Results:
- Infections can lead to osteoarticular and soft tissue issues.
- Malignancies may present with rheumatic symptoms through invasion or paraneoplastic effects.
Conclusions:
- Increased awareness of infectious and malignant causes is crucial for primary care physicians.
- Early screening and intervention based on risk factors improve patient prognosis.
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