Related Experiment Video
Updated: Feb 10, 2026

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis
Published on: April 17, 2017
Using of aerodynamic droplet breakup for mass-spectrometric analysis
Viktor V Pervukhin1, Dmitriy G Sheven1
1Nikolaev Institute of Inorganic Chemistry of SB RAS, Acad. Lavrentieva Ave., 3, 630090 Novosibirsk, Russia.
Abstract:
The method of ionization by aerodynamic droplet breakup is considered for applications in mass spectrometric analysis. It is assumed that Aerodynamic Breakup Droplet Ionization (ABDI) occurs in a tube linking the region of atmospheric pressure to the area of weak vacuum. The possibility of ionization of solutions of organic compounds and organometallic complexes is shown. As test compounds were chosen: heroin (as an example of organic compounds) and organometallic complexes of ruthenium and copper, dissolved in water or acetonitrile. The quality of the ABDI spectra depends on the analyte. In general, the analytes ionized by the ABDI method show a great propensity to form dimers and trimers. ABDI system can be easily installed on any mass spectrometer with inlet at atmospheric pressure and used as an additional method. Since compounds prone to degradation in ESI analysis are better suited for ABDI analysis, this seems useful.
Related Concept Videos
Mass Spectrometry: Complex Analysis
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
Atomic Mass
Molar Mass
Formula Mass and Mole Concepts of Compounds
Dimensional Analysis
Conversion Factors and Dimensional Analysis
The unit...
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...

