Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Association Areas of the Cortex01:21

Association Areas of the Cortex

9.5K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.5K
Sustainable Development01:43

Sustainable Development

15.2K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.2K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

7.7K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
7.7K
Nursing Clinical Information System01:27

Nursing Clinical Information System

1.3K
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.3K
Clinical Trials01:16

Clinical Trials

10.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.9K
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

2.8K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From community to policy: a frontline model for dementia assessment and brain health.

Frontiers in dementia·2026
Same author

A high-dimensional atlas of parvalbumin interneuron soma morphology in mouse visual and somatosensory cortex.

Frontiers in neuroscience·2026
Same author

Sex as a biological variable in amblyopia: implications for developmental plasticity and treatment.

Frontiers in neuroscience·2026
Same author

Anatomical and molecular development of the human primary visual cortex.

Frontiers in cellular neuroscience·2024
Same author

Purinergic Signalling Mediates Aberrant Excitability of Developing Neuronal Circuits in the Fmr1 Knockout Mouse Model.

Molecular neurobiology·2024
Same author

Corrigendum: A Practical Guide to Sparse <i>k</i>-Means Clustering for Studying Molecular Development of the Human Brain.

Frontiers in neuroscience·2022

Related Experiment Video

Updated: Feb 10, 2026

Human Egg Maturity Assessment and Its Clinical Application
08:51

Human Egg Maturity Assessment and Its Clinical Application

Published on: August 19, 2019

20.2K

The development of human visual cortex and clinical implications.

Caitlin R Siu1, Kathryn M Murphy1,2

  • 1McMaster Integrative Neuroscience Discovery and Study (MiNDS) Program, McMaster University, Hamilton, ON, Canada.

Eye and Brain
|May 16, 2018
PubMed
Summary
This summary is machine-generated.

Human primary visual cortex (V1) development involves five distinct stages from infancy through adulthood. Understanding these stages is crucial for developing new treatments for vision disorders affecting neuroplasticity.

Keywords:
GABAergicamblyopiadevelopmentglutamatergichuman visual cortexreceptorssynaptic plasticity

More Related Videos

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

11.3K
Organotypic Cultures of Adult Human Cortex as an Ex vivo Model for Human Stem Cell Transplantation and Validation
07:16

Organotypic Cultures of Adult Human Cortex as an Ex vivo Model for Human Stem Cell Transplantation and Validation

Published on: December 9, 2022

3.0K

Related Experiment Videos

Last Updated: Feb 10, 2026

Human Egg Maturity Assessment and Its Clinical Application
08:51

Human Egg Maturity Assessment and Its Clinical Application

Published on: August 19, 2019

20.2K
Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

11.3K
Organotypic Cultures of Adult Human Cortex as an Ex vivo Model for Human Stem Cell Transplantation and Validation
07:16

Organotypic Cultures of Adult Human Cortex as an Ex vivo Model for Human Stem Cell Transplantation and Validation

Published on: December 9, 2022

3.0K

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Ophthalmology

Background:

  • The primary visual cortex (V1) is critical for visual processing, with normal development reliant on binocular vision.
  • Age-related vision loss is associated with neurobiological changes in V1, but human V1 mechanisms remain understudied.
  • Limited knowledge of human V1 neurobiology hinders clinical translation of treatments from animal models.

Purpose of the Study:

  • To characterize neurobiological mechanisms in human V1 that regulate visual perception and neuroplasticity.
  • To identify and describe developmental stages of human V1 across the lifespan.

Main Methods:

  • Human V1 tissue analysis to identify and characterize neurobiological mechanisms.
  • Correlation of identified developmental stages with established visual and anatomical milestones.

Main Results:

  • Identification of five distinct developmental stages in human V1, spanning from infancy to old age.
  • Characterization of the expression of key neurobiological mechanisms regulating visual perception and plasticity throughout these stages.

Conclusions:

  • Human V1 undergoes significant developmental changes throughout life, not just during early critical periods.
  • Understanding these lifelong developmental stages is essential for advancing treatments for visual disorders.
  • This research provides a framework for translating findings on V1 neuroplasticity into effective clinical interventions.