Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pericarditis I: Introduction01:22

Pericarditis I: Introduction

432
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
432
Radical Reactivity: Nucleophilic Radicals01:16

Radical Reactivity: Nucleophilic Radicals

2.7K
Radicals adjacent to electron-donating groups are called nucleophilic radicals. These radicals readily react with electrophilic alkenes. The SOMO–LUMO interactions are the driving force for the reaction, where the high-energy SOMO of the electron-rich, nucleophilic radicals interacts with the low-energy LUMO of the electron-deficient, electrophilic alkenes. Such SOMO–LUMO interactions are the basis of reactive radical traps, affecting the selectivity in radical reactions. For...
2.7K
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

369
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
369
Pericarditis IV: Nursing Management01:25

Pericarditis IV: Nursing Management

382
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
382
Radicals01:27

Radicals

747
Roots, often written as radicals, identify the quantity that must be raised to a specific exponent to produce a given value. A radical expression consists of two main components: the radicand, which is the value placed inside the root symbol, and the index, which indicates the degree of the root being taken. The notation n√a indicates the principal nth root of a. If n equals 2, the operation is the square root, while n = 3 defines the cube root. When n is even, a negative radicand does...
747
Radical Reactivity: Electrophilic Radicals01:02

Radical Reactivity: Electrophilic Radicals

2.5K
Radicals adjacent to electron‐withdrawing groups are called electrophilic radicals. These radicals readily react with nucleophilic alkenes. For example, the malonate radical, in which the radical center is flanked by two electron‐withdrawing groups, reacts readily with butyl vinyl ether, which consists of an electron‐donating oxygen substituent. The reaction between electrophilic malonate radical and nucleophilic vinyl ether is favored because the radical has a...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genomic Medicine Sweden: Advancing precision medicine at the national level.

Journal of internal medicine·2026
Same author

Mineralocorticoid Receptor Antagonists With an Acylurea as a Key Polar Interaction Motif.

ChemMedChem·2026
Same author

Determinants and relationships of climate change, climate change hazards, mental health, and well-being: a systematic review.

Frontiers in psychiatry·2025
Same author

Real-time genome imaging of host interactions in adeno-associated virus genome release.

iScience·2025
Same author

High incidence of permanent pacemaker after Cox-maze IV and mitral valve surgery: a nationwide registry-based study.

Interdisciplinary cardiovascular and thoracic surgery·2025
Same author

Causes and clinical impact of initial misdiagnosis of acute type A aortic dissection.

European heart journal open·2025

Related Experiment Video

Updated: Feb 10, 2026

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
08:23

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats

Published on: March 13, 2012

60.7K

Radical pericardiectomy for chronic constrictive pericarditis.

Shahab Nozohoor1, Maria Johansson1, Bansi Koul1

  • 1Department of Cardiothoracic Surgery, Skane University Hospital, Clinical Sciences, Lund University, Lund, Sweden.

Journal of Cardiac Surgery
|May 16, 2018
PubMed
Summary

Radical pericardiectomy significantly improves survival and functional class in constrictive pericarditis patients compared to sub-total pericardiectomy. This procedure offers better long-term outcomes for patients with this heart condition.

Keywords:
cardiac functioncardiac reoperationoutcomespericardium

More Related Videos

Automated Gait Analysis in Mice with Chronic Constriction Injury
06:49

Automated Gait Analysis in Mice with Chronic Constriction Injury

Published on: October 17, 2017

10.8K
Author Spotlight: Utilizing Infraorbital Nerve Ligation in Mice for Investigating Trigeminal Neuropathic Pain and Treatment Strategies
05:38

Author Spotlight: Utilizing Infraorbital Nerve Ligation in Mice for Investigating Trigeminal Neuropathic Pain and Treatment Strategies

Published on: March 8, 2024

2.9K

Related Experiment Videos

Last Updated: Feb 10, 2026

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
08:23

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats

Published on: March 13, 2012

60.7K
Automated Gait Analysis in Mice with Chronic Constriction Injury
06:49

Automated Gait Analysis in Mice with Chronic Constriction Injury

Published on: October 17, 2017

10.8K
Author Spotlight: Utilizing Infraorbital Nerve Ligation in Mice for Investigating Trigeminal Neuropathic Pain and Treatment Strategies
05:38

Author Spotlight: Utilizing Infraorbital Nerve Ligation in Mice for Investigating Trigeminal Neuropathic Pain and Treatment Strategies

Published on: March 8, 2024

2.9K

Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Cardiac Surgery

Background:

  • Chronic constrictive pericarditis impairs cardiac function and patient quality of life.
  • Pericardiectomy is a surgical option to treat constrictive pericarditis.
  • The extent of pericardiectomy (radical vs. sub-total) may impact patient outcomes.

Purpose of the Study:

  • To compare the efficacy of radical pericardiectomy versus sub-total pericardiectomy.
  • To evaluate the impact of surgical approach on patient survival and functional status.
  • To assess long-term outcomes in patients with chronic constrictive pericarditis.

Main Methods:

  • Retrospective study of 41 patients with chronic constrictive pericarditis from 1991-2016.
  • Patients were divided into two groups: radical pericardiectomy (n=24) and sub-total pericardiectomy (n=17).
  • Outcomes assessed included early and long-term survival, New York Heart Association (NYHA) functional class, and left ventricular ejection fraction, with 100% follow-up.

Main Results:

  • Radical pericardiectomy demonstrated significantly higher 10-year survival rates (94%) compared to sub-total pericardiectomy (55%) (P=0.014).
  • In the idiopathic subgroup, radical pericardiectomy also showed increased long-term survival (P=0.001).
  • Postoperative functional improvement was superior with radical pericardiectomy, with 85-94% of patients achieving NYHA class I or II up to 25 years versus 53-63% for sub-total pericardiectomy.

Conclusions:

  • Radical pericardiectomy is associated with superior long-term survival in patients with chronic constrictive pericarditis.
  • The radical approach leads to better clinical functional improvement compared to sub-total pericardiectomy.
  • This study supports radical pericardiectomy as the preferred surgical strategy for chronic constrictive pericarditis.