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Mohs Micrographic Surgery: Development, Technique, and Applications in Cutaneous Malignancies
Eillen Luisa A Chen1, Divya Srivastava1, Rajiv I Nijhawan1
1Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.
Seminars in Plastic Surgery
|May 17, 2018
Summary
Mohs micrographic surgery (MMS) provides the highest skin cancer cure rates by examining all margins. This specialized technique maximizes tissue preservation for optimal cosmetic results and is cost-effective for specific indications.
Area of Science:
- Dermatology
- Surgical Oncology
- Pathology
Background:
- Mohs micrographic surgery (MMS) is a specialized technique for skin cancer treatment.
- It ensures complete tumor removal through complete margin assessment.
- MMS aims to preserve healthy tissue, optimizing cosmetic and functional outcomes.
Purpose of the Study:
- To discuss the development and procedural steps of Mohs micrographic surgery.
- To outline the indications for employing MMS in treating skin malignancies.
- To review the application of MMS for various skin cancers, including BCC, SCC, and melanoma in situ.
Main Methods:
- Histological examination of the entire peripheral and deep margins during surgery.
- Sequential removal and microscopic analysis of tissue layers.
- Application of MMS for specific skin malignancies like basal cell carcinoma and squamous cell carcinoma.
Main Results:
- MMS achieves the highest cure rates for skin malignancies.
- Maximal preservation of uninvolved adjacent tissue is a key outcome.
- The technique is cost-effective when indicated.
Conclusions:
- Mohs micrographic surgery is a highly effective treatment for skin cancer.
- It offers superior oncologic control and tissue preservation.
- Appropriate patient selection is crucial for successful MMS outcomes.
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