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Correlation between Allergic Rhinitis and Laryngopharyngeal Reflux
Sami Alharethy1, Abdulsalam Baqays2, Tamer A Mesallam2,3
1Division of Facial Plastic Surgery, Department of Otolaryngology, Head & Neck Surgery, King Abdulaziz University Hospital, King Saud University, P.O. Box 245, Riyadh 11411, Saudi Arabia.
Laryngopharyngeal reflux (LPR) may worsen allergy symptoms. This study found a significant association between LPR and higher allergic rhinitis scores, suggesting a link between these conditions.
Area of Science:
- Otolaryngology
- Allergy and Immunology
Background:
- Laryngopharyngeal reflux (LPR) presents with nonspecific symptoms.
- LPR symptoms can overlap with allergic conditions like allergic rhinitis and laryngitis.
- Limited research exists on the correlation between LPR and allergic rhinitis/laryngitis.
Purpose of the Study:
- To investigate the correlation between laryngopharyngeal reflux and allergic rhinitis/laryngitis.
- To explore the relationship between LPR diagnostic measures and allergic rhinitis symptom scores.
Main Methods:
- 126 patients with suspected LPR were enrolled.
- Patients were categorized into LPR positive and negative groups.
- 24-hour oropharyngeal pH monitoring and the Score for Allergic Rhinitis (SFAR) were utilized.
Main Results:
- LPR positive patients had significantly higher SFAR scores (p < 0.0001).
- A significant correlation was observed between the Ryan score and SFAR total score and its symptom items (r = 0.35-0.5).
Conclusions:
- Laryngopharyngeal reflux appears to intensify patients' self-reported allergic manifestations.
- An association exists between laryngopharyngeal reflux and allergic rhinitis/laryngitis.
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