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Related Concept Videos

Guidelines for Sketching a Curve01:23

Guidelines for Sketching a Curve

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Curve sketching is a systematic method for understanding the overall behavior of a function by analyzing its key mathematical features. A function defines a curve on the coordinate plane, where the horizontal axis represents the input variable and the vertical axis represents the output. The process begins by determining the domain, which specifies the set of input values for which the function is defined and establishes the horizontal extent of the graph.Intercepts with the horizontal and...
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When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
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Guidelines for Nursing Documentation I01:30

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Quality documentation and reporting share essential characteristics that ensure they are practical and valuable resources for those who use them. These characteristics are:
Factual:  
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Guidelines for Nursing Documentation II01:26

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Effective documentation is an integral part of nursing practice. Here are some essential guidelines to follow when documenting patient care:
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Related Experiment Video

Updated: Feb 10, 2026

Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis
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Update in sepsis guidelines: what is really new?

Rebecca Plevin1, Rachael Callcut1

  • 1Department of Surgery, University of California San Francisco, San Francisco, California, USA.

Trauma Surgery & Acute Care Open
|May 17, 2018
PubMed
Summary

Sepsis is a life-threatening condition causing significant mortality and healthcare costs. Early identification and treatment are key, but patient variability necessitates precision health approaches for better outcomes.

Area of Science:

  • Critical Care Medicine
  • Infectious Diseases
  • Public Health

Background:

  • Sepsis causes over 200,000 deaths annually in the USA, with a 30% in-hospital mortality rate.
  • Annual healthcare costs exceed $24 billion, escalating with an aging population.
  • Previous sepsis definitions lacked clarity, prompting a revised consensus.

Purpose of the Study:

  • To present the 2016 updated clinical practice guidelines for sepsis management.
  • To introduce a new definition of sepsis and novel screening tools.
  • To highlight the need for precision medicine in sepsis treatment.

Main Methods:

  • Convening of the Third International Consensus Definitions Task Force.
  • Review and update of clinical practice guidelines for severe sepsis and septic shock.
Keywords:
sepsisseptic shock

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  • Development of the quick Sequential [Sepsis-related] Organ Failure Assessment (qSOFA) score for rapid screening.

    • Main Results:

    • Sepsis redefined as life-threatening organ dysfunction from a dysregulated host response to infection.
    • The Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score aids rapid identification.
    • Early identification, a 3-hour care bundle, and prompt antibiotics correlate with mortality reduction.

    Conclusions:

    • Despite advances, sepsis mortality reduction remains challenging due to patient variability.
    • The new definition and qSOFA score aim to improve early detection.
    • Precision health approaches are crucial for advancing sepsis treatment and improving survival rates.