Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anatomy of the Adrenal Glands01:17

Anatomy of the Adrenal Glands

4.9K
The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
4.9K
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

3.3K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
3.3K
Hormones of the Adrenal Glands01:31

Hormones of the Adrenal Glands

5.5K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
5.5K
Data Reporting and Recording01:24

Data Reporting and Recording

5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
Types of Reports I: Hands-off Report01:25

Types of Reports I: Hands-off Report

1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla01:27

Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla

3.0K
The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
3.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Quantification of Ki-67 in PitNET (pituitary neuroendocrine tumors)/adenomas].

Pathologie (Heidelberg, Germany)·2024
Same author

[Xanthogranulomatous adrenalitis : A rare and difficult differential diagnosis of adrenal gland tumors].

Pathologie (Heidelberg, Germany)·2024
Same author

Inflammatory and Infectious Disorders in Endocrine Pathology.

Endocrine pathology·2023
Same author

Multiple tumorous lesions of the pituitary gland.

Hormones (Athens, Greece)·2022
Same author

ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers.

Science advances·2022
Same author

ACTH-secreting pituitary carcinoma with TP53, NF1, ATRX and PTEN mutations Case report and review of the literature.

Endocrine·2022
Same journal

Distinct ALK Expression Patterns Are Associated with Canonical and Noncanonical STRN::ALK Transcript Architectures in Oncocytic Thyroid Neoplasms.

Endocrine pathology·2026
Same journal

Neuroendocrine Tumors of the Gallbladder: A Multicenter Case Series and Systematic Literature Review Indicating Predominantly Non-Aggressive Tumor Behavior and a Common Association with Cholesterol Polyps and Cholesterolosis.

Endocrine pathology·2026
Same journal

Genomic Catastrophe Defines the Evolutionary Trajectory of Adrenocortical Carcinoma.

Endocrine pathology·2026
Same journal

Three-Tier Prognostic Stratification of Lung Carcinoids (NET G1-G2-G3) by Multivariable, Data-Driven Integration of Ki-67 and Mitotic Count.

Endocrine pathology·2026
Same journal

Impact of Molecular Testing on Surgical Decision-Making in Indeterminate Thyroid Nodules: A Global Meta-Analysis Across Test Generations.

Endocrine pathology·2026
Same journal

Molecular Profiling of Digestive Grade 3 Neuroendocrine Tumors Reveals a Shared Molecular Framework with Lower-Grade Tumors, Marked Heterogeneity, and Therapeutic Opportunities.

Endocrine pathology·2026
See all related articles

Related Experiment Video

Updated: Feb 10, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
06:08

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

24.3K

IgG4-Associated Adrenalitis-a Case Report.

Wolfgang Saeger1, Bernd Lohe2, Christina Luise Engels2

  • 1Institute of Pathology of the University of Hamburg, Martinistraße 52, UKE, 20246, Hamburg, Germany. w.saeger@uke.de.

Endocrine Pathology
|May 17, 2018
PubMed
Summary
This summary is machine-generated.

This study reports the first case of active IgG4-associated adrenalitis, identified in a patient who underwent adrenalectomy for a large adrenal tumor. This condition may precede adrenal calcifying fibrous tumors.

Keywords:
AdrenalAdrenalitisCase reportIgG4-association

More Related Videos

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
08:37

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands

Published on: October 2, 2018

25.4K
Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

10.1K

Related Experiment Videos

Last Updated: Feb 10, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
06:08

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

24.3K
Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
08:37

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands

Published on: October 2, 2018

25.4K
Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

10.1K

Area of Science:

  • Endocrinology
  • Pathology
  • Immunology

Background:

  • Adrenal tumors can present with diverse histopathological findings.
  • Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory condition characterized by IgG4-producing plasma cells.

Observation:

  • A 67-year-old male patient underwent adrenalectomy for a 100 mm adrenal tumor.
  • Histopathological examination revealed inflammation, fibrosis, and infiltrates of lymphocytes and plasmacytes.
  • Immunoreactivity for IgG and IgG4 was noted in the specimen.

Findings:

  • The adrenal specimen was diagnosed as active IgG4-associated adrenalitis.
  • This represents the first reported case of active IgG4-associated adrenalitis.
  • The findings suggest this may be a precursor lesion to adrenal calcifying fibrous tumors.

Implications:

  • This discovery expands the spectrum of IgG4-related diseases affecting the adrenal glands.
  • Recognizing active IgG4-associated adrenalitis is crucial for understanding its potential progression to calcifying fibrous tumors.
  • Further research is warranted to elucidate the pathogenesis and clinical significance of IgG4-associated adrenalitis.