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Updated: Feb 10, 2026

Minimal Erythema Dose MED Testing
Published on: May 28, 2013
Erythema multiforme after orf virus infection
Angella López-Cedeño1, Gustavo Cañedo2, Nicole Knöpfel1
1Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Abstract:
The case of a 6-year-old boy with multiple, target-shaped lesions and a crusted nodule on his right index finger is presented. Based on clinical findings and the patient's recent contact with sheep and goats, a diagnosis of orf disease associated with erythema multiforme was suspected. Microscopy studies confirmed the presence of parapoxvirus in the primary lesion. Orf-induced erythema multiforme is a rare complication of orf in children, possibly related to the presence of orf virus DNA in erythema multiforme lesions.
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