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Updated: Feb 10, 2026

Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells
Published on: April 14, 2010
Overview of Gene Expression Analysis: Transcriptomics
Nalini Raghavachari1, Natàlia Garcia-Reyero2
1Division of Geriatrics and Clinical Gerontology, National Institute on Aging, Bethesda, MD, USA. nraghava88@gmail.com.
Abstract:
Currently, the study of the transcriptome is widely used to interpret the functional elements of the genome and molecular constituents of cells and tissues in an effort to unravel biological pathways associated with development and disease. The advent of technologies is now enabling the study of such comprehensive transcriptional characterization of mRNA, miRNA, lncRNA, and small RNA in a robust and successful manner. Transcriptomic strategies are gaining momentum across diverse areas of biological, plant sciences, medical, clinical, and pharmaceutical research for biomarker discovery, and disease diagnosis and prognosis.
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