[Paraneoplastic syndromes : multiple aspects]

Knowledge of paraneoplastic syndromes, and above all their diversity, is very important in terms of clinical application because they often forerun the oncologic diagnosis and thereby may be a tell-tale sign. Recognizing them could allow an early diagnosis at the beginning of the disease or at the relapse. The diversity of these syndromes is an additional problem and clinicians must be aware of this differential diagnosis. Conventional therapeutic management could be insufficient, and recognizing the diagnosis allows to adapt the therapeutic strategy. In this review, we will try to illustrate the diversity of the most frequent paraneoplastic syndromes, present their oncologic connections and their clinical features.