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Substance Use among the Patients with First Episode Psychosis.

M S Ahsan1, M S Mullick, K Begum

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Substance use is double in first-episode psychosis patients in Bangladesh, with cannabis being the most common cause. Current substance abuse was not observed in this initial study group.

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Area of Science:

  • Psychiatry
  • Neuroscience
  • Public Health

Background:

  • Substance Use Disorder is prevalent in Bangladesh.
  • Substance use is linked to psychosis development and modification.
  • First-Episode Psychosis (FEP) requires understanding of contributing factors.

Purpose of the Study:

  • To determine the proportion of substance use among FEP patients in Dhaka, Bangladesh.
  • To compare substance use prevalence between FEP patients and healthy controls.
  • To identify common substances associated with psychosis in this population.

Main Methods:

  • Cross-sectional study conducted at two tertiary hospitals in Dhaka.
  • Inclusion of 50 consecutive FEP patients and 50 healthy controls.
  • Data collection on demographics, occupation, and lifetime/current substance use.

Main Results:

  • Lifetime substance use was twice as common in FEP patients compared to controls.
  • Cannabis was the most frequently identified substance associated with psychosis.
  • No current substance abuse or dependence was reported among the FEP patients in the study.

Conclusions:

  • Substance use, particularly cannabis, is significantly associated with first-episode psychosis in Bangladesh.
  • Further prospective research with larger sample sizes is needed to explore the long-term outcomes.
  • Findings highlight the importance of screening for substance use in FEP patients.