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Updated: Feb 10, 2026

Author Spotlight: High-Resolution Imaging of Mouse Neonate Brains – A Micro-CT Protocol with Lugol's Solution Contrast Agent
Published on: May 19, 2023
Motion compensated micro-CT reconstruction for in-situ analysis of dynamic processes
Thomas De Schryver1,2,3, Manuel Dierick1,2,3, Marjolein Heyndrickx1,2
1Radiation Physics research group, Dept. Physics and Astronomy, Ghent University, Proeftuinstraat 86/N12, 9000, Gent, Belgium.
Abstract:
This work presents a framework to exploit the synergy between Digital Volume Correlation (DVC) and iterative CT reconstruction to enhance the quality of high-resolution dynamic X-ray CT (4D-µCT) and obtain quantitative results from the acquired dataset in the form of 3D strain maps which can be directly correlated to the material properties. Furthermore, we show that the developed framework is capable of strongly reducing motion artifacts even in a dataset containing a single 360° rotation.
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