Related Experiment Video

Updated: Feb 10, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.8K

[Chronic kidney disease in children up to 2 years of age - a single center data analysis]

Kinga Musiał1, Marta Sałamacha1, Sylwia Gralec1

  • 1Medical University of Wrocław, Poland: Chair and Department of Pediatric Nephrology.

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|May 19, 2018
PubMed

Insights

Urinary tract anomalies are the main cause of pediatric chronic kidney disease (CKD) across all ages. However, etiological factors like perinatal acute kidney injury in younger children and glomerulopathies in older children show age-related differences.

Area of Science:

  • Pediatric Nephrology
  • Renal Disease Etiology
  • Chronic Kidney Disease (CKD)

Background:

  • Urinary tract anomalies are the primary cause of chronic kidney disease (CKD) in children.
  • Limited research exists on age-specific etiological differences in pediatric CKD.

Purpose of the Study:

  • To compare the causes of CKD in hospitalized children.
  • To analyze age and gender as factors influencing CKD etiology in pediatric patients.

Main Methods:

  • Retrospective analysis of 174 pediatric patients (0-18 years) with CKD from 2011-2017.
  • Patients were divided into two age groups: 0-2 years (Group A, n=45) and 2-18 years (Group B, n=129).

Main Results:

  • Urinary tract anomalies were the leading cause of CKD in both groups (66.7% in Group A, 48.8% in Group B).
  • In younger children (Group A), perinatal acute kidney injury (17.8%) and hereditary renal disorders (8.9%) were significant factors.
  • In older children (Group B), glomerulopathies (16.3%) and hereditary renal disorders (15.5%) were the next most common causes after urinary tract anomalies.

Conclusions:

  • Urinary tract anomalies are the predominant cause of pediatric CKD, regardless of age.
  • Male predominance was observed only in children under 2 years old.
  • Acute kidney injury, particularly perinatal, is a key factor in young children, while glomerulopathies and hereditary disorders are significant in older children.

Keywords:
acute kidney injurychronic kidney diseaseglomerulopathieshereditary renal disordersurinary tract anomalies

More Related Videos

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat08:50

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

Published on: July 3, 2013

24.4K
Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools11:29

Measuring the Functional Abilities of Children Aged 3-6 Years Old with Observational Methods and Computer Tools

Published on: June 20, 2020

9.8K

Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
762
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
679
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
483
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
410
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.6K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
4.7K