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Updated: Feb 10, 2026

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds
Published on: January 7, 2019
Patellofemoral Cartilage Repair
Alexandre Barbieri Mestriner1,2, Jakob Ackermann3, Andreas H Gomoll3
1Cartilage Repair Center, Department of Orthopaedic Surgery, Harvard Medical School, Brigham and Women's Hospital, 850 Boylston Street, Suite 120, Chestnut Hill, MA, 02467, USA. abmestriner@hotmail.com.
This review details cartilage repair techniques for the patellofemoral joint (PFJ), offering an algorithm for treatment. Current methods like autologous chondrocyte implantation and osteochondral allografts show promise for cartilage defects.
Area of Science:
- Orthopedics
- Regenerative Medicine
- Sports Medicine
Background:
- Cartilage defects in the patellofemoral joint (PFJ) are common and can lead to pain and dysfunction.
- Current treatments aim to delay or avoid arthroplasty and improve symptoms in young patients.
Purpose of the Study:
- To review established and novel cartilage repair techniques for PFJ defects.
- To present an algorithm for managing PFJ cartilage defects based on anatomical considerations.
Main Methods:
- Review of current literature on PFJ cartilage repair.
- Analysis of outcomes for various surgical techniques.
Main Results:
- Autologous chondrocyte implantation is effective for chondral lesions; osteochondral allografts for osteochondral defects.
- Tibial tubercle osteotomy can improve outcomes in cases of patellar malalignment.
- Particulated cartilage and bone marrow aspirate concentrate are emerging treatments.
Conclusions:
- Careful patient selection, surgical technique, and addressing concomitant abnormalities are crucial for successful PFJ cartilage repair.
- Further comparative studies and investigation of new techniques are necessary.
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