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Updated: Feb 10, 2026

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds
Published on: January 7, 2019
Patellofemoral Cartilage Repair
Alexandre Barbieri Mestriner1,2, Jakob Ackermann3, Andreas H Gomoll3
1Cartilage Repair Center, Department of Orthopaedic Surgery, Harvard Medical School, Brigham and Women's Hospital, 850 Boylston Street, Suite 120, Chestnut Hill, MA, 02467, USA. abmestriner@hotmail.com.
Purpose Of Review:
This review provides an overview of well-established and newly developed cartilage repair techniques for cartilage defects in the patellofemoral joint (PFJ). An algorithm will be presented for approaching cartilage defects considering the distinct anatomy of both the patellar and trochlear articular surfaces.
Recent Findings:
Recent studies on cartilage repair in the PFJ have demonstrated improved outcomes in an attempt to delay or obviate the need for arthroplasty, and improve symptoms in young patients. While autologous chondrocyte implantation shows good and excellent outcomes for chondral lesions, osteochondral defects are adequately addressed with osteochondral allograft transplantation. In case of patellar malalignment, concomitant tibial tubercle osteotomy can significantly improve outcomes. Particulated cartilage and bone marrow aspirate concentrate are potential new alternative treatments for cartilage repair, currently in early clinical studies. Due to the frequency of concomitant anatomic abnormalities in the PFJ, a thorough clinical examination combined with careful indication for each procedure in each individual patient combined with meticulous surgical technique is central to achieve satisfying outcomes. Additional comparative studies of cartilage repair procedures, as well as investigation of newer techniques, are needed.
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