Microendoscopy-Assisted Minimally Invasive Versus Open Transforaminal Lumbar Interbody Fusion for Lumbar Degenerative

Yang Yang1, Zhong-Yu Liu1, Liang-Ming Zhang1

  • 1Department of Spine Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

World Neurosurgery
|May 21, 2018
PubMed
Abstract

Insights

Microendoscopy-assisted minimally invasive (MIS) transforaminal lumbar interbody fusion (TLIF) shows comparable 5-year outcomes to open TLIF. MIS-TLIF offers benefits like reduced injury and faster recovery, despite longer surgical times.

Area of Science:

  • Spinal surgery
  • Minimally invasive techniques
  • Fusion procedures

Background:

  • Transforaminal lumbar interbody fusion (TLIF) is a common spinal procedure.
  • Minimally invasive surgery (MIS) aims to reduce surgical trauma.
  • Microendoscopy offers enhanced visualization during MIS.

Purpose of the Study:

  • To compare 5-year outcomes of microendoscopy-assisted MIS-TLIF versus open TLIF.
  • To evaluate perioperative parameters and long-term functional results.

Main Methods:

  • Sixty patients underwent single-level MIS or open TLIF (30 per group).
  • Perioperative data, pain scores (VAS), functional scores (JOA, ODI), and fusion rates were assessed.
  • Long-term outcomes included modified MacNab criteria and adjacent segment degeneration.

Main Results:

  • MIS-TLIF showed reduced blood loss and earlier ambulation but longer operative time and fluoroscopy.
  • Both groups improved significantly in pain and function scores at 5 years.
  • Fusion rates and adjacent segment degeneration were similar between groups.

Conclusions:

  • Microendoscopy-assisted MIS-TLIF is comparable to open TLIF at 5 years.
  • MIS-TLIF provides benefits of less iatrogenic injury and quicker recovery.
  • Long-term functional outcomes and fusion success are equivalent.

Related Concept Videos

Nuclear Fusion02:45

Nuclear Fusion

The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
33.9K
5-Number Summary01:04

5-Number Summary

In a dataset, the 5-number summary includes the minimum data value, the data value of the first quartile, the median data value or data value of the second quartile, the data value of the third quartile, and the maximum data value. These 5 data values can be visualized as a box and whisker plot.
In a box plot, the minimum and maximum data values represent the lower and upper whiskers in the graph, and the median is designated as the center of the box in the chart. The first quartile and third...
5.7K
Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
11.0K
Outcomes of Glycolysis01:13

Outcomes of Glycolysis

Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
107.6K
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
4.0K
Tagging and Fusion Proteins01:24

Tagging and Fusion Proteins

Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...
8.5K