Related Experiment Video
Updated: Feb 10, 2026

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats
Published on: February 14, 2022
Analysis of variability of R-R intervals for the diagnosis of atrial fibrillation: A new algorithm
Taishi Matsui1, Ryo Shinozaki1, Eiichi Watanabe2
1Department of Development, UNION TOOL CO., Niigata, Japan.
Abstract:
Differences in successive R-R intervals (RRIs) were normalized by RRIs before and after the indexing beats (normalized DRs) in individuals with normal sinus rhythm (NSR) and 98.89% of normalized DRs were found to distribute within mean±0.100 (≒mean±3SD), whereas 73.47% were out of this range in atrial fibrillation (AF). When 7 out 20 normalized DRs fell outside of 0.000±0.100, NSR (n=129) and AF (n=108) could be discriminated with high sensitivity, specificity, and predictive values (>99.0% for all). This method will be used in detecting AF candidates from a small number of heart beats or arterial pulses.
More Related Videos
Related Concept Videos
Variability: Analysis
The range is a simple measure of variability, indicating the difference between the highest and...
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
Amyloid Fibrils
Prediction Intervals
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y.
Fibril-associated Collagen
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
Confidence Intervals
A...

