Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

685
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
685
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

1.1K
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.1K
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

1.1K
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
1.1K
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

579
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
579
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

353
Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
353
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

249
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
249

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis and characterization of soquelitinib a selective ITK inhibitor that modulates tumor immunity.

npj drug discovery·2026
Same author

Update on Therapy for Non-Infectious Scleritis.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Re: Ghoraba et al.: Incidence of endophthalmitis after cataract surgery in the setting of uveitis and immunosuppressive therapy within the IRIS® Registry (Ophthalmology. 2025;132:1253-1259).

Ophthalmology·2026
Same author

Isolation and identification of neuroprotective compounds from <i>Morus alba</i> L. root bark against NMDA-induced retinal degeneration.

Natural product research·2026
Same author

Impact of Socioeconomic Disadvantage on Clinical Outcomes of Inflammatory Eye Disease Patients Requiring Systemic Immunosuppression.

Ocular immunology and inflammation·2026
Same author

Comprehensive Adult Medical Eye Evaluation Preferred Practice Pattern®.

Ophthalmology·2026

Related Experiment Video

Updated: Feb 10, 2026

Dissection, Culture and Analysis of Primary Cranial Neural Crest Cells from Mouse for the Study of Neural Crest Cell Delamination and Migration
09:33

Dissection, Culture and Analysis of Primary Cranial Neural Crest Cells from Mouse for the Study of Neural Crest Cell Delamination and Migration

Published on: October 3, 2019

11.6K

Retinal vasculitis associated with CREST syndrome.

Sungjae Yang1,2, Laura J Kopplin3, James T Rosenbaum2,4,5

  • 1Department of Ophthalmology, Gangneung Asan Hospital, Ulsan University, Gangneung, South Korea.

American Journal of Ophthalmology Case Reports
|May 22, 2018
PubMed
Summary

This study highlights retinal vasculitis as a new ocular complication of CREST syndrome. Early immunomodulatory treatment may help prevent vision loss in affected patients.

Keywords:
CREST syndromeRetinal vasculitis

More Related Videos

Author Spotlight: Retinal Neuroscience Studies with Volume Electron Microscopy
03:48

Author Spotlight: Retinal Neuroscience Studies with Volume Electron Microscopy

Published on: May 24, 2024

1.0K
Preparation of Mouse Retinal Cryo-sections for Immunohistochemistry
05:25

Preparation of Mouse Retinal Cryo-sections for Immunohistochemistry

Published on: July 1, 2019

30.5K

Related Experiment Videos

Last Updated: Feb 10, 2026

Dissection, Culture and Analysis of Primary Cranial Neural Crest Cells from Mouse for the Study of Neural Crest Cell Delamination and Migration
09:33

Dissection, Culture and Analysis of Primary Cranial Neural Crest Cells from Mouse for the Study of Neural Crest Cell Delamination and Migration

Published on: October 3, 2019

11.6K
Author Spotlight: Retinal Neuroscience Studies with Volume Electron Microscopy
03:48

Author Spotlight: Retinal Neuroscience Studies with Volume Electron Microscopy

Published on: May 24, 2024

1.0K
Preparation of Mouse Retinal Cryo-sections for Immunohistochemistry
05:25

Preparation of Mouse Retinal Cryo-sections for Immunohistochemistry

Published on: July 1, 2019

30.5K

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • CREST syndrome is a rare autoimmune disorder affecting connective tissues.
  • Ocular manifestations of CREST syndrome are not well-documented.
  • Retinal vasculitis is an inflammation of retinal blood vessels.

Observation:

  • Two patients with CREST syndrome presented with distinct ocular inflammatory conditions.
  • Patient 1 exhibited unilateral panuveitis with significant retinal vasculitis and prior uveitis.
  • Patient 2 experienced a branch retinal artery occlusion and bilateral retinal vasculitis.

Findings:

  • Retinal vasculitis is a previously unreported ocular finding in patients with CREST syndrome.
  • Both patients demonstrated inflammatory ocular disease requiring systemic treatment.

Implications:

  • Retinal vasculitis should be considered in the differential diagnosis of ocular inflammation in patients with CREST syndrome.
  • Prompt initiation of immunomodulatory therapy, such as prednisone and mycophenolate mofetil, may be crucial in mitigating ocular morbidity.
  • This finding expands the spectrum of known ocular complications associated with CREST syndrome.