Related Experiment Video

Updated: Feb 10, 2026

Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents
05:46

Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents

Published on: January 24, 2013

22.1K

[CIRCADIAN DEPENDENCE OF PARACETAMOL HEPATOTOXICITY IN RATS.]

K O Kal'ko, S M Drogovoz, A Yu Pozdnyakova

    Eksperimental'Naia I Klinicheskaia Farmakologiia
    |May 22, 2018
    PubMed

    More Related Videos

    Circadian Entrainment of Drosophila Melanogaster07:12

    Circadian Entrainment of Drosophila Melanogaster

    Published on: June 3, 2020

    4.8K
    Human Circadian Phenotyping and Diurnal Performance Testing in the Real World10:16

    Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

    Published on: April 7, 2020

    9.1K

    Related Concept Videos

    Circadian Rhythms and Gene Regulation02:19

    Circadian Rhythms and Gene Regulation

    The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
    4.6K
    Frequency-dependent Selection01:21

    Frequency-dependent Selection

    When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
    24.2K
    Drug Dependence01:17

    Drug Dependence

    Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
    1.7K
    Contact-dependent Signaling01:19

    Contact-dependent Signaling

    Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
    Gap Junctions
    In animal cells, gap junctions are formed...
    47.6K
    Temperature Dependence on Reaction Rate02:55

    Temperature Dependence on Reaction Rate

    The Collision Theory
    Atoms, molecules, or ions must collide before they can react with each other. Atoms must be close together to form chemical bonds. This premise is the basis for a theory that explains many observations regarding chemical kinetics, including factors affecting reaction rates.
    The collision theory is based on the postulates that (i) the reaction rate is proportional to the rate of reactant collisions, (ii) the reacting species collide in an orientation allowing contact between...
    89.3K
    Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

    Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

    Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
    The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
    375