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GENimmune NV.

Geert Maertens1, Lydie Meheus1, Fred Shapiro2

  • 1GENimmune NV, Technologiepark 6, Gent, Belgium. bd@genimmune.be.

Personalized Medicine
|May 23, 2018
PubMed
Summary

GENimmune NV is developing novel immune therapeutics for chronic infectious diseases. Their strategy uses rational vaccine design with polyepitopes to optimize immune response against viruses like hepatitis B and C.

Keywords:
biomanufacturingimmune therapeuticsmonoclonal antibodypolyepitopetherapeutic vaccine

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Area of Science:

  • Biopharmaceutical research
  • Immunology
  • Vaccinology

Background:

  • Chronic infectious diseases often involve inadequate immune responses.
  • GENimmune NV is a new biopharmaceutical company focused on immune therapeutics.
  • Existing treatments may not fully address the complexities of chronic infections.

Purpose of the Study:

  • To develop novel immune therapeutics targeting chronic infectious diseases.
  • To optimize the human immune response through rational vaccine design.
  • To create therapeutic vaccine candidates for hepatitis B, hepatitis C, and human papillomavirus.

Main Methods:

  • Utilizing a strategy based on rational vaccine design.
  • Employing polyepitopes that consider immunological plasticity and viral diversity.
  • Leveraging an early-stage pipeline of therapeutic vaccine candidates.

Main Results:

  • Development of early-stage therapeutic vaccine candidates.
  • Establishment of a biomanufacturing unit for R&D support.
  • Proven track record in providing third-party contract services.

Conclusions:

  • GENimmune NV presents an original approach to medical treatment for chronic infectious diseases.
  • The company's polyepitope strategy aims to enhance immune response efficacy.
  • Further development of vaccine candidates is ongoing.