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Published on: June 12, 2021
Percutaneous intentional intra-luminal-assisted recanalization (PILAR technique) of challenging chronic total
Stephanie Volpi1, Amine Chouiter2, Francois Saucy3
1Cardio-Thoracic and Vascular Unit, Department of radiology, Centre Hospitalo-Universitaire Vaudois, Rue de Bugnon 46, CH-1011, Lausanne, Switzerland. stephanie.volpi@chuv.ch.
Insights
High-frequency vibrational device (HFVD)-assisted percutaneous intentional intraluminal-assisted recanalization (PILAR) offers a safe and effective first-line approach for challenging chronic total occlusions (CTOs). This technique demonstrates high success rates in recanalizing complex lesions, improving patient outcomes.
Area of Science:
- Cardiovascular Interventions
- Vascular Surgery
- Medical Devices
Background:
- Peripheral chronic total occlusions (CTOs) present significant recanalization challenges, particularly with in-stent, pre-stent, or heavily calcified lesions.
- A high-frequency vibrational device (HFVD) has emerged as a potential tool for guidewire-refractory CTOs.
Purpose of the Study:
- To evaluate the safety and efficacy of HFVD as a primary treatment for complex CTOs.
- To establish the percutaneous intentional intraluminal-assisted recanalization (PILAR) technique using HFVD.
Main Methods:
- Fifty-two patients with challenging CTOs (pre-stent, in-stent, calcified) underwent treatment with HFVD.
- Technical success was defined by successful CTO crossing with HFVD; intraluminal crossing was a secondary outcome.
- Safety endpoints included thromboembolism and perforation, with 3-month and 1-year follow-up for patency.
Main Results:
- Technical success rate for CTO recanalization was 90%, with 83% achieving intraluminal crossing.
- The average recanalized length was 91 mm; one thromboembolic event occurred and was successfully treated.
- Primary patency rates were 92% at 3 months and 79% at 1 year.
Conclusions:
- HFVD-based PILAR is a safe and effective strategy for recanalizing challenging CTOs, including long, calcified, in-stent, and pre-stent lesions.
- Intraluminal recanalization is the preferred approach for complex CTOs.
- First-line use of HFVD-assisted recanalization defines the PILAR technique, offering high success rates.
Objectives:
Recanalization of peripheral chronic total occlusions (CTO) is technically challenging especially in cases of in-stent and/or pre-stent and heavily calcified lesions. A high-frequency vibrational device (HFVD) was first used as a secondary-intention device in CTO recanalizations when they were refractory to a guidewire. The aim of this study was to assess the safety and efficacy of the HFVD as a first-line treatment for challenging CTOs and thus to define the percutaneous intentional intraluminal-assisted recanalization (PILAR) technique.
Methods:
Fifty-two patients were treated with the HFVD. Only challenging CTOs were included: 7 pre-stent, 7 in-stent, and 38 highly calcified CTOs. Technical success was defined as the ability to cross the CTO using the HFVD. Secondary outcome was defined as successful intraluminal crossing. Safety endpoints were procedure-related thromboembolism or perforation. Patients were followed up at 3 months and 1 year.
Results:
The technical success rate for recanalization was 90%, of which 83% were intraluminal. The mean recanalized length was 91 ± 44 mm. One thromboembolic complication occurred, which was subsequently treated with thromboaspiration. Three-month and 1-year primary patency rates were 92% and 79%, respectively.
Conclusions:
HFVD-based PILAR is a safe and effective technique for in-stent or pre-stent CTO recanalization of long and calcified lesions.
Key Points:
• Intraluminal recanalization is the preferred procedure in heavily calcified or pre-/in-stent CTO. • First-line use of assisted intraluminal recanalization for CTO defines the PILAR technique. • HFVD-based PILAR is safe and provides a high success rate for challenging CTO recanalization.
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