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Prosthetic Joint Infections: an Update
1Department of Medicine, Section of Infectious Diseases, University of the Philippines, Philippine General Hospital, Taft Ave., Manila, Philippines.
Current Infectious Disease Reports
|May 24, 2018
Summary
Diagnosing prosthetic joint infection (PJI) requires a high clinical suspicion and multiple tests. Research explores new diagnostic tools and optimal antimicrobial therapy durations for PJI management.
Area of Science:
- Orthopedic surgery
- Infectious diseases
- Diagnostic microbiology
Background:
- Prosthetic joint infection (PJI) is a rare but severe complication often misdiagnosed.
- Accurate and timely diagnosis of PJI is crucial for effective patient outcomes.
Purpose of the Study:
- To clarify key aspects of prosthetic joint infection (PJI) diagnosis.
- To review current antimicrobial therapies for PJI.
- To provide guidance on PJI management.
Main Methods:
- Review of current research on PJI diagnostic biomarkers.
- Evaluation of molecular techniques and implant sonication for PJI diagnosis.
- Analysis of antimicrobial therapy durations and suppressional treatment.
Main Results:
- A high index of suspicion combined with multimodal testing aids PJI diagnosis.
- Biomarkers, molecular methods, and sonication are adjuncts to traditional methods.
- Optimal antimicrobial therapy duration and role of chronic suppressive therapy require further study.
- Evidence suggests revising practices for dental prophylaxis and asymptomatic bacteriuria treatment in PJI prevention.
Conclusions:
- Timely PJI diagnosis relies on clinical suspicion and comprehensive testing.
- Further research, including randomized controlled trials, is needed for antimicrobial therapy optimization.
- Current evidence challenges routine dental prophylaxis and treatment of asymptomatic bacteriuria for PJI prevention.
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