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Updated: Feb 10, 2026

Evaluation of a Universal Nested Reverse Transcription Polymerase Chain Reaction for the Detection of Lyssaviruses
Published on: May 2, 2019
Molecularly imprinted nanoparticles for inhibiting ribonuclease in reverse transcriptase polymerase chain reaction
Xiaotong Feng1, Jon Ashley, Tongchang Zhou
1Department of Micro- and Nanotechnology, Technical University of Denmark, Ørsteds Plads, DK- 2800 Kgs, Lyngby, Denmark. Sun.Yi@nanotech.dtu.dk.
Abstract:
Molecularly imprinted nanoparticles (nanoMIPs) are synthesized via a solid-phase approach using RNase as the template. The feasibility of employing the nanoMIPs as RNase inhibitor is successfully demonstrated in reverse transcriptase polymerase chain reaction (RT-PCR) assays, suggesting the tailor-made nanomaterials are very promising for use in routine biological assays.
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