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Updated: Feb 10, 2026

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
Published on: February 7, 2025
No association of moon phase with stroke occurrence
Jori O Ruuskanen1,2, Jussi O T Sipilä1,2,3, Päivi Rautava4,5
1a Division of Clinical Neurosciences , Turku University Hospital , Turku , Finland.
This study found no link between moon phases and stroke hospitalizations or mortality. Research on moon cycles and stroke occurrence remains inconclusive, with this study showing no significant associations.
Area of Science:
- Neurology
- Chronobiology
- Public Health
Background:
- Stroke occurrence is linked to sleep disorders and circadian rhythms.
- Lunar cycles may influence physiological processes, but their effect on stroke is understudied.
- Previous research on moon phases and stroke is rare and inconclusive.
Purpose of the Study:
- To investigate the association between moon phases and stroke hospitalizations.
- To examine the relationship between moon phases and in-hospital mortality for stroke patients.
- To analyze nationwide stroke data in Finland over a 10-year period.
Main Methods:
- Utilized nationwide Finnish stroke hospitalization data from 2004-2014.
- Included patients aged 18+ with ischemic stroke (IS) or intracerebral hemorrhage (ICH).
- Employed Poisson regression modeling with moon phase, year, and season as independent variables.
Main Results:
- No statistically significant association was found between moon phases and stroke occurrence (IS or ICH).
- In-hospital mortality rates for stroke did not differ across various moon phases.
- Subgroup analyses by sex, age, and season also revealed no moon phase-related differences.
Conclusions:
- Moon phases do not appear to influence the occurrence or in-hospital mortality of ischemic stroke or intracerebral hemorrhage.
- This large-scale, decade-long study provides robust evidence against a link between lunar cycles and stroke outcomes.
- Findings suggest that factors other than lunar cycles are primary drivers of stroke incidence and mortality.
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