Related Experiment Video
Updated: Feb 10, 2026
Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
Upper gastrointestinal endoscopy applied in pediatrics: endoscopic and histological findings, including Helicobacter
Diego Soares Coca1, Carolina Manna Santos1, Osmar Silvio Garcia de Oliveira1
1Endoscopy Service, Hospital Ana Costa. São Paulo, Brazil.
Insights
Pediatric upper digestive endoscopy is crucial for diagnosing conditions like esophagitis and gastritis in children. This study highlights the importance of specialized centers for safe and effective pediatric endoscopic procedures.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Endoscopy
- Pediatric Surgery
Background:
- Upper digestive endoscopy in children is a specialized procedure with unique indications and challenges.
- Understanding the spectrum of diseases and outcomes in pediatric endoscopy is essential for improving patient care.
Purpose of the Study:
- To analyze the endoscopic and histological findings in pediatric patients undergoing upper digestive endoscopy.
- To determine the incidence of Helicobacter pylori and other gastrointestinal diseases in this population.
- To evaluate the indications, characteristics, and outcomes of therapeutic endoscopic interventions in children.
Main Methods:
- A retrospective analysis of 25 upper digestive endoscopies performed in children aged six months to 11 years.
- Diagnostic endoscopies with serial biopsies of the esophagus, stomach, and duodenum were conducted in 200 patients.
- Therapeutic procedures were performed in 26 patients, including gastrostomies, foreign body removal, and esophageal dilatation.
Main Results:
- Esophagitis, gastritis, and duodenitis were the most common endoscopic findings.
- Helicobacter pylori infection was detected in 13% of the pediatric patients tested.
- Therapeutic interventions included gastrostomy placement, foreign body extraction, and esophageal dilation.
Conclusions:
- Pediatric endoscopy is a vital subspecialty within digestive endoscopy.
- A robust institutional infrastructure is paramount for ensuring the safety and efficacy of pediatric endoscopic procedures.
- The ability to manage potential complications is a critical aspect of pediatric endoscopy services.
Objective:
To present and discuss the endoscopic and histological results, as well as the incidence of Helicobacter pylori and other diseases, indications and characteristics of upper digestive endoscopies performed in children.
Material And Methods:
Twenty-five endoscopies were performed in children aged six months to 11 years (mean 7.69 years), from February 2013 to January 2016. In 200 patients, endoscopies were diagnostic and serial biopsies were performed (esophagus, stomach and duodenum), in 120 of them.
Results:
The indication of endoscopy was diagnosed in 88.89% of the patients, and in 26 patients, a therapeutic procedure was performed. The most frequent endoscopic findings were esophagitis in 49 patients, gastritis in 84 and duodenitis in 16 patients. Four duodenal ulcers were diagnosed. In the therapeutic endoscopies, six gastrostomies were performed, 14 foreign body withdrawals, five nasoenteral tube passages and esophageal dilatation. The H. pylori survey was performed by anatomopathological method and was positive in 26 (13%) of the 200 patients in whom it was searched.
Conclusion:
pediatric endoscopy is an important niche of the digestive endoscopy, where it is important to emphasize the relevance of the institutional structure that performs these procedures, in order to conduct them safely, being able to treat possible and feasible complications.
Related Concept Videos
01:20Histology of the Gastrointestinal (GI) Tract
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
01:16Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
01:28Endoscopic Procedures III: Video Capsule Endoscopy
01:26Anatomy of the Gastrointestinal System
Here's a detailed walkthrough of this complex system:
01:03Finding the Center of Gravity
01:29Cardiovascular System Abnormal Findings I: Inspection and Palpation
Abnormal findings observed during an inspection